Figure 7.
Calcium homeostasis and protease genes do not suppress motility defects in TDP-43WT animals. There was no significant suppression of TDP-43WT motility defects by Ca2+ or protease gene mutations. p < 0.001 for TDP-43A315T versus TDP-43WT. TDP-43A315T, n = 81; TDP-43WT, n = 65; TDP-43WT; crt-1(bz30), n = 71; TDP-43WT; itr-1(sa73), n = 71; TDP-43WT; unc-68(e540), n = 60; TDP-43WT; cnx-1(nr2010), n = 61; TDP-43WT; tra-3(ok2207), n = 71; TDP-43WT; asp-4(ok2693), n = 115.