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. 2014 Oct 1;61(1):108–118. doi: 10.1002/hep.27242

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© 2014 The Authors. Hepatology published by Wiley Periodicals, Inc., on behalf of the American Association for the Study of Liver Diseases.

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Fig. 8 — Accumulation of PNPLA3 and CGI-58 protein on hepatic lipid droplets of PNPLA3^WTTg and PNPLA3^148MTg mice. Lipid droplets and mRNA were prepared from livers of 11-week-old male mice after 4 weeks on a high-sucrose diet. (A) Relative levels of endogenous and human PNPLA3 and CGI-58 mRNA in wild-type (+/+), PNPLA3^WTTg, and PNPLA3^148MTg transgenic mice. (B) Immunoblot analysis of lipid droplet proteins from wild-type (+/+), PNPLA3^WTTg, and PNPLA3^148MTg transgenic mice. *P < 0.01. The experiment was repeated twice and the results were similar.