Figure 2.

KLRG1^loCD127^hi effector CD8⁺ T cells are enriched due to extrinsic factors in Bim^−/− mice. (a) As depicted in the figure, 5 × 10³ WT or Bim^−/− P14 Thy1.1⁺ CD8⁺ T cells were transferred into congenic WT or Bim^−/− mice (n=4–6 recipient mice per genotype per timepoint) and infected with LCMV 1 day later. (b and c) Graphs show percentages of Thy1.1⁺ P14 or Thy1.2⁺ endogenous cells within GP33⁺ CD8⁺ T cells on day 10 (b) or day 20 (c) after infection. (d and e) Graphs show percentages (d) or total numbers (e) of KLRG1^hiCD127^lo or KLRG1^loCD127^hi subsets within the total Thy1.1⁺ P14 cells analyzed on day 20 after infection. Data are representative of two independent experiments