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Exosome structure and function. (a) Exosome biogenesis and function: once released, exosomes can travel through biological fluids (e.g. serum, lymph) and furthermore, they can be internalized by cells from nearby tissues, or more so, reach body sites very far from their tissue of origin. (b) Main classes of molecules included in the exosomal cargo. MT, mitochondria; MVB, multivesicular bodies
