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. 2014 Sep 19;22(1):34–45. doi: 10.1038/cdd.2014.130

Table 2. Exosomes application in immune-driven vaccines.

Cancer type Results Reference
Melanoma Exosomes from dendritic cells promote the differentiation of melanoma-specific T cells and thus produce IFN-γ lymphocytes 57
Leukemia Inhibition of tumor growth by lysis of cancer cells 86
Lymphoma Heat-shocked exosomes against neoplastic cells 83
Leukemia Induction of spleen cell proliferation and inhibition of cancer cells 87
Lung cancer Anticancer response of dendritic cell-derived exosomes 94
Pancreatic cancer Induction of apoptosis via Notch signaling 112
Pancreatic cancer Induction of apoptosis via PI3K/Akt/GSK-3β pathway 113
Melanoma IL-I5Rα-dependent cell proliferation 81
Lymphoma Inhibition of tumor growth 88