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. 2014 Nov 21;46(11):e122. doi: 10.1038/emm.2014.72

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Copyright © 2014 KSBMB.

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/

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Potential targets and inhibitors for (lymph)angiogenic factors in AML. As target molecules involved in lymphangiogenesis, several factors have been applied in clinical studies. AML focused agents typically target dual or multiple protein kinases, and then chemotherapy combined trials with inhibitors to effectively inhibit AML blasts.