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In vitro selectivity profile of selected TNKS inhibitors. No inhibitors have so far been profiled using activity assays with ARTD8, ARTD9, ARTD13, ARTD15, or ARTD16. NI subsite, nicotinamide subsite; ADE subsite, adenosine subsite. IC50 values have been gathered from the literature [15, 23, 68, 157, 159-168].
