Figure 6.

The splicing efficiency of dmpi8 also modulates arousal to non-photic sensory stimulation. (A-D) Flies were kept in LD at 25°C for 5 days, and during the last 3 days of LD, flies were subjected to a brief mechanical stimulation at either ZT6 or ZT18 (as indicated by vertical arrows and right of panels); a third group served as non-treated controls. Shown are normalized group averages of total sleep for p{dmper/8:8} (WT; blue line) or p{dmper/M2M1} (red line) flies that were either treated (A,B) or not treated (C,D) with a brief mechanical stimulation. Results are shown for females but similar results were obtained with males (data not shown). For each value shown, data from at least 16 flies were used to generate the sleep profiles shown. To facilitate comparison, the highest value for total sleep was set to 100 and all other values were normalized.