Supplemental Table 2.
Comparison between participants with and without incident MetS
| Characteristics | Without incident MetS (n=12 478) | With incident MetS (n=2428) | p-value1 |
|---|---|---|---|
| Uric acid | 6.0 (0.01) | 6.3 (0.02) | <0.001 |
| Age (y) | 44.5 (0.01) | 44.6 (0.03) | 0.001 |
| Body mass index (kg/m2) | 23.6 (0.02) | 25.6 (0.05) | <0.001 |
| Waist circumference (cm) | 81.8 (0.06) | 87.2 (0.13) | <0.001 |
| Systolic BP (mmHg) | 110.8 (0.12) | 115.8 (0.28) | <0.001 |
| Diastolic BP (mmHg) | 76.4 (0.08) | 79.9 (0.18) | <0.001 |
| Total cholesterol (mg/dL) | 191.8 (0.27) | 201.4 (0.63) | <0.001 |
| Triglyceride (mg/dL) | 121.2 (0.55) | 167.4 (1.73) | <0.001 |
| HDL-cholesterol (mg/dL) | 52.7 (0.09) | 47.9 (0.18) | <0.001 |
| LDL-cholesterol (mg/dL) | 112.7 (0.24) | 120.1 (0.53) | <0.001 |
| Fasting serum glucose (mg/dL) | 95.5 (0.11) | 101.0 (0.37) | <0.001 |
| HOMA-IR | 1.95 (0.01) | 2.47 (0.02) | <0.001 |
| Insulin (μU/dL) | 8.2 (0.03) | 9.9 (0.07) | <0.001 |
| Serum creatinine (mg/dL) | 1.13 (0.001) | 1.14 (0.002) | <0.001 |
| eGFR (mL/min per 1.73 m2) | 79.8 (0.08) | 78.2 (0.18) | <0.001 |
| Aspartate aminotransferase (U/L) | 24.9 (0.14) | 26.9 (0.24) | <0.001 |
| Alanine aminotransferase (U/L) | 27.5 (0.21) | 34.1 (0.42) | <0.001 |
| γ-glutamyltransferase (U/L) | 35.7 (0.30) | 50.7 (0.99) | <0.001 |
| hsCRP (mg/L) | 0.12 (0.004) | 0.15 (0.009) | 0.02 |
| Current smoker (%) | 38.4 (0.4) | 45.0 (1.0) | 0.02 |
| Alcohol intake (%) | 12.7 (0.3) | 15.9 (0.7) | 0.03 |
| Regular exercise (%) | 19.2 (0.3) | 21.0 (0.8) | 0.03 |
| Diabetes mellitus (%) | 2.3 (0.1) | 5.7 (0.5) | 0.06 |
| Hypertension (%) | 12.5 (0.3) | 23.5 (0.9) | <0.001 |
Values are presented as means (standard error), or percentages (standard error).
MetS, metabolic syndrome; BP, blood pressure; HDL, high-density lipoprotein; LDL, low-density lipoprotein; HOMA-IR, homeostasis model assessment of insulin resistance; eGFR, estimated glomerular filtration rate; hsCRP, high-sensitivity C-reactive protein.
1
p-value was tested by multiple logistic regression models after adjusting for 5 year-age group.