Table 2. Subsequent memory (‘DM’)-related group activity after ROI-based alignment.
| Cluster size | Cluster Puncorr | Alpha (simulated) | Peak T | Peak location | Template x, y, z {mm} | Side |
|---|---|---|---|---|---|---|
| Group activity for 1.5 mm smoothing | ||||||
| 21 | 0.007 | <0.10 | 4.60 | pyramidal CA1 (body) | 31.1, 22.1, −21.1 | R |
| 33 | 0.001 | <0.02 | 4.58 | EC & sub (head) | −14.6, 41.2, −26.0 | L |
| 16 | 0.017 | <0.25 | 4.31 | CA1/presub.(head) | 15.1, 38.1, −23.4 | R |
| 17 | 0.014 | <0.20 | 4.20 | CA2/3-DG (posterior body) | 23.9, 14.8, −12.7 | R |
| Group activity for 2.4 mm smoothing | ||||||
| 96 | 0.001 | <0.01 | 5.94 | CA1/presub. (head) | 15.1, 38.1, −23.4 | R |
| 72 | 0.003 | <0.01 | 5.51 | EC | −13.8, 41.6, −25.3 | L |
| 25 | 0.053 | <0.20 | 4.90 | CA2/3-DG (posterior body) | 25.5, 13.7, −13.1 | R |
| 44 | 0.014 | <0.05 | 4.49 | pyramidal CA1 (body) | 31.1, 22.5, −22.2 | R |
| 37 | 0.022 | <0.10 | 4.31 | Sub/CA1 (body) | 22.3, 23.5, −21.9 | R |
| 57 | 0.006 | <0.02 | 4.05 | EC | 13.5, 34.5, −26.9 | R |
DG, dentate gyrus; EC, entorhinal cortex; R, right; ROI, region of interest L, left.
Functional data were smoothed with two different kernels to allow for higher specificity and higher sensitivity, respectively. Hippocampal and entorhinal subregions showing group-level activation (at Pvoxel level<0.005; k1.5 mm≥15 voxels and k2.4 mm≥25 voxels, N=19) for the DM contrast (difference due to memory: remembered>forgotten). Alphas were simulated with 3dClustSim (AFNI). Note that clusters that would not survive correction at low smoothing (highlighted in italics; for example, pyramidal layers in CA1) become significant with higher smoothing.