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(a) In cotton fibres, DELLA proteins bind to HOX3 to prevent its binding to other HD-ZIP transcription factors, repressing their transcriptional activation to target genes. (b) GAs trigger degradation of DELLAs, releasing HOX3 protein to interact with other HD proteins, such as HD1, allowing the activation of target genes, including RDL1 and EXPA1, to promote cotton fibre elongation.
