2a.
Baseline Characteristics: Single Dose (Part 1): All Randomized Subjects
| Placebo (n =14) | 0.03 mg/kg (n = 6) | 0.06 mg/kg (n = 6) | 0.15 mg/kg (n = 6) | 0.30 mg/kg (n = 6) | 0.60 mg/kg (n = 7) | 1.00 mg/kg (n = 6) | 1.50 mg/kg (n = 6) | |
|---|---|---|---|---|---|---|---|---|
| Age (years) | 32.9 (6.7) | 37.3 (11.2) | 32.3 (12.3) | 39.3 (11.3) | 35.2 (11.8) | 37.6 (4.5) | 35.0 (7.1) | 31.8 (13.6) |
| Race, n (%) | ||||||||
| White | 12 (86) | 6 (100) | 5 (83) | 5 (83) | 4 (67) | 2 (29) | 4 (67) | 5 (83) |
| Black or African American | 2 (14) | 0 | 1 (17) | 1 (17) | 2 (33) | 4 (57) | 2 (33) | 0 |
| Asian | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other | 0 | 0 | 0 | 0 | 0 | 1 (14) | 0 | 1 (17) |
| Body weight (kg) | 105.0 (17.3) | 96.6 (13.7) | 93.2 (8.9) | 95.1 (13.1) | 89.4 (10.6) | 97.0 (8.8) | 101.5 (15.1) | 97.8 (12.3) |
| BMI (kg/m2) | 32.1 (3.1) | 32.2 (4.8) | 30.8 (2.5) | 31.0 (3.4) | 30.4 (2.0) | 32.3 (2.1) | 33.0 (4.2) | 31.2 (3.5) |
Data are mean (standard deviation) unless otherwise specified.
BMI, body mass index.