Table 2.

Clinical outcomes and cerebral blood flow indices measured during 90-day follow-up

	Total (n=43)	Cerebrolysin (n=22)	Placebo (n=21)	P-value
NIHSS score
Baseline	14 (13, 16)	14 (13, 15)	14 (12, 16)	0.432
Day 30	12 (10, 13)	11 (10, 12)	12 (10, 14)	0.092
Day 60	10.5 (9, 12)	10 (9, 11)	12 (10, 14)	0.008
Day 90	10 (8, 11)	9 (8, 10)	11 (10, 13.5)	0.001
Velocity of right MCA, cm/s
Baseline	48 (40, 57)	47 (39, 50)	48 (41, 64)	0.343
Day 30	49 (43, 56)	45 (38, 52)	53 (49, 57)	0.033
Day 60	50 (44, 55)	46 (42, 52)	51 (49, 57)	0.055
Day 90	50 (44, 55)	48 (41, 53)	54.5 (49, 56.5)	0.065
Velocity of left MCA, cm/s
Baseline	47 (40, 56)	49 (38, 56)	45 (40, 50)	0.806
Day 30	47 (42, 55)	46 (40, 51)	47 (43, 59)	0.768
Day 60	48.5 (41, 57)	47 (41, 52)	50 (45, 58)	0.789
Day 90	50 (43, 55)	49 (43, 52)	50 (48, 55)	0.638
Velocity of basilar artery, cm/s
Baseline	30 (21, 42)	31.5 (25, 37)	28 (18, 47)	0.504
Day 30	30 (20, 42)	31 (25, 38)	28 (20, 48)	0.610
Day 60	30 (25, 40)	30 (27, 36)	30 (20, 49)	0.341
Day 90	33 (28, 43)	32 (29, 38)	36.5 (27, 46)	0.657
Right MCA PI
Baseline	0.9 (0.8, 1.1)	0.85 (0.7, 1.1)	1 (0.8, 1.2)	0.364
Day 30	1 (0.8, 1.1)	0.85 (0.8, 1)	1.1 (0.9, 1.2)	0.010
Day 60	1 (0.8, 1.1)	0.9 (0.8, 1)	1.1 (1, 1.2)	0.001
Day 90	1 (0.9, 1.1)	0.9 (0.8, 1.1)	1 (1, 1.2)	0.014
Left MCA PI
Baseline	1 (0.8, 1.2)	1 (0.8, 1.1)	1.1 (0.8, 1.3)	0.345
Day 30	1 (0.8, 1.1)	1 (0.8, 1.1)	1.1 (0.9, 1.2)	0.286
Day 60	1 (0.9, 1.1)	1 (0.9, 1.1)	1 (0.9, 1.1)	0.627
Day 90	1 (0.9, 1.2)	1 (0.8, 1.1)	1 (0.9, 1.2)	0.277
Basilar artery PI
Baseline	1 (0.8, 1.1)	1 (0.9, 1.1)	0.9 (0.8, 1.1)	0.576
Day 30	1 (0.8, 1.1)	1 (0.8, 1.1)	0.9 (0.8, 1)	0.384
Day 60	0.95 (0.9, 1.1)	0.9 (0.9, 1.1)	1 (0.9, 1.1)	0.931
Day 90	1 (0.8, 1.1)	1 (0.9, 1.1)	0.95 (0.8, 1.1)	0.828

Abbreviations: MCA, middle cerebral artery; NIHSS, National Institutes of Health Stroke Scale; PI, pulsatility index.