Table 1.
Diagnostic Groups | |||
---|---|---|---|
Characteristic | MCI (N = 28) |
Control (N = 26) |
All Subjects (N = 54) |
Age — yr | 68.1 ± 11.8 | 67.3 ± 11.7 | 68.2 ± 11.4 |
Education — yr | 16.2 ± 2.9 | 17.7 ± 2.6 | 17.1 ± 3.0 |
Female sex — no. (%)* | 16 (57) | 9 (34) | 25 (46) |
AD family history—no (%) | 12 (43) | 13 (50) | 25 (46) |
APOE-4 carrier— no. (%)† | 9 (36) | 13 (50) | 22 (43) |
Mini Mental State Exam‡ | 27.6 ± 1.8 | 29.1 ± 1.3 | 28.2 ± 1.7 |
Estimated Verbal IQ§ | 110.3 ± 8.4 | 117.3 ± 6.1 | 113.6 ± 8.1 |
HRSD-21 | 1.9 ± 2.4 | 2.3 ± 2.4 | 2.2 ± 2.4 |
MCI = Mild Cognitive Impairment; AD = Alzheimer’s disease; APOE-4 = Apolipoprotein Epsilon-4; HRSD = Hamilton Rating Scale for Depression 21-item version.
X2(1) = 3.92, p = 0.05;
APOE-4 missing for 3 MCI subjects;
t(53) = 4.4, p < 0.0001.
Intelligence Quotient estimated using adult reading tests (the Wechsler Test of Adult Reading, N = 8; or the National Adult Reading Test, N = 41); t(47) = 3.32, p = .002. N = 5 missing values,