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. Author manuscript; available in PMC: 2014 Dec 11.
Published in final edited form as: Int J Geriatr Psychiatry. 2012 Mar 1;27(10):1017–1027. doi: 10.1002/gps.2816

Table 2.

Diagnostic Group and Memory Domain Z Scores of the FDDNP Clusters.

FDDNP Signal Clusters
Diagnostic Group No. of subjects per cluster
LG HF/PA HT/PC
Normal cognition 19 7 1
MCI 5 17 7
 MCI-A 4 7 2
 MCI-A+ 1 10 5
Mean (SD) Domain Z Scores for Clusters*
LG HF/PA HT/PC
Memory .59 (.70) −.33 (.81) −.43 (.56)
Executive .48 (.49) −.42 (1.04) −.28(1.02)

LG = Low Global; HF/PA = High frontal/parietal and medial temporal signal with intermediate signal in temporal and posterior cingulate; HT/PC = High lateral temporal/posterior cingulate. MCI-A = single domain amnestic mild cognitive impairment; MCI-A+ = multiple domain amnestic mild cognitive impairment.

*

Lower (more negative) Z scores represent poorer performances.

Memory Domain: [F(2,46) = 8.07, p = .001; LG vs HF/PA: t(46) = 3.82, p = .0004; LG vs HT/PC: t(46) = 2.39, p = .02];

Executive Domain [F(2,46) = 5.25, p = .01; LG vs HF/PA: t(46) = 3.24, p = .002]