Table 3.
Number and Cognitive Status of Subjects in FDG-PET visual rating and FDDNP-PET Subgroups.
FDDNP-PET Pattern | |||
---|---|---|---|
Visual Rating of FDG-PET Pattern | LG N = 23 |
HT/PC N = 7 |
HF/PA N = 24 |
AD-like* | 5 (3/1/1) | 2 (0/1/1) | 14 (1/5/8) |
Non-AD-like* | 18 (15/3/0) | 5 (1/1/3) | 10 (6/2/2) |
PET = Positron Emission Tomography; FDG = 2-deoxy-2-[F-18]fluoro-D-glucose; FDDNP = 2-(1-{6-[(2-[F-18]fluoroethyl)(methyl) amino]-2-naphthyl} ethylidene)malononitrile; AD-like = Alzheimer’s disease like FDG-PET pattern; LG = Low global FDDNP binding; HT/PC = high FDDNP binding in medial and lateral temporal and posterior cingulate regions; HF/PA = high FDDNP binding in frontal, parietal and medial temporal regions.
Frequencies are for Total Subjects (Cognitively Normal/MCI-A/MCI-A+).