Figure 1. Networks 1(A), 2 (B) and 4 (C) generated by IPA and associated with up- and down-regulated genes in the category visual system and development in the retina of nanoceria injected Vldlr−/− mouse.
The solid arrow between molecules depicts experimentally proven direct relationship. A dashed line depicts indirect interaction based on experimental evidence. Up-regulated genes are shown in red color and down-regulated in green color. Intensity of color indicates the degree of up- or down-regulation. Genes associated with visual system and development functions are annotated (Fx).