Table 2.

List of differentially expressed genes (≥1.5 fold) in the retina of Vldlr−/− mice after nanoceria treatment. Data are expressed as fold change of nanoceria (CeO₂) injected Vldlr−/− mice (n=6) to Wt mice (n=4). *P<0.05

Gene name	Gene	CeO2-Vldlr/Wt
	symbol	Fold change	p-value
Up-regulated genes
Fibroblast growth factor 17	Fgf17	3.1	0.1742
Interleukin 19	Il19	2.9	0.3090
Interleukin 5	IL5	2.5	0.2253
Fibroblast growth factor 6	Fgf6	2.3	0.0740
Fibroblast growth factor 15	Fgf15	2.3	0.3014
Fibroblast growth factor 18	Fgf18	2.2	0.1461
Fibroblast growth factor 16	Fgf16	1.8	0.0282*
Interleukin 2	IL2	1.8	0.1670
Interleukin 24	IL24	1.8	0.3723
Interleukin 3	IL3	1.7	0.1864
Growth hormone	Gh	1.5	0.0890
Interleukin 24	Il24	1.5	0.0638
Down-regulated genes
Vascular endothelial growth factor A	Vegfa	−6.2	0.0009*
Interleukin 7	Il7	−4.8	0.0410*
Leukemia inhibitory factor	Lif	−4.4	0.0192*
Leptin	Lep	−3.1	0.1090
Interleukin 9	Il9	−3.1	0.0073*
Fibroblast growth factor 9	Fgf9	−3.1	0.0871
Epidermal growth factor	Egf	−2.4	0.0770
Growth arrest specific 6	Gas6	−2.3	0.0104*
Interleukin 12b	Il12b	−2.1	0.0750
Ephrin A3	Efna3	−2.0	0.1440
Interferon 1	Ifne1	−1.9	0.2610
Cardiotrophin-like cytokine factor 1	Clc	−1.8	0.2421
Fibroblast growth factor 7	Fgf7	−1.8	0.1030
Neuregulin 1	Nrg1	−1.7	0.0051*
Neuregulin 3	Nrg3	−1.6	0.1652
Thymic stromal lymphopoietin	Tslp	−1.6	0.1081
Fibroblast growth factor 21	Fgf21	−1.6	0.1000
Fibroblast growth factor 22	Fgf22	−1.6	0.2646
Fibroblast growth factor 2	Fgf2	−1.6	0.0670
Zinc finger protein 91	Zfp91	−1.6	0.0113*
Angiopoietin 2	Angpt2	−1.5	0.1080
Fibroblast growth factor1	Fgf1	−1.5	0.0261*
Neuregulin 4	Nrg4	−1.5	0.0630