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. 2014 Dec 11;10(12):e1003991. doi: 10.1371/journal.pcbi.1003991

Figure 3. Time-courses of the phosphorylated nuclear p53 (green) and nuclear Mdm2 (red) in response to two different Nutlin extra-cellular concentrations in RKO and SJSA-1 cells.

Figure 3

Solid lines represent medians, and dotted lines first and third quartiles. The Nutlin exposure begins at Inline graphic. Left column: PTEN feedback loop is active; right column: PTEN feedback loop is inactive.