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. 2014 Dec 11;10(12):e1004011. doi: 10.1371/journal.pcbi.1004011

Table 1. Ionic model parameters used in parameter sensitivity analysis.

Parameter Description
gNa Maximal fast Na+ current conductance
gNaL Maximal late Na+ current conductance
gCaL Maximal L-type Ca2+ current conductance
τf L-type Ca2+ current voltage-dependent inactivation time constant
τfCa Maximal L-type Ca2+ current calcium-dependent inactivation time constant
gK1 Maximal inward rectifier K+ current conductance
gKr Maximal rapidly activating delayed rectifier K+ current conductance
gKs Maximal slowly activating delayed rectifier K+ current conductance
gKur Maximal ultrarapid delayed rectifier K+ current conductance
gto Maximal transient outward K+ current conductance
IbarNCX Maximal Na+/Ca2+ exchanger current
ks SR Ca2+ release rate constant
kim Transition rate constant for the RyR
kom Transition rate constant for the RyR
kiCa Baseline inactivation rate constant for the RyR without luminal SR Ca2+ dependence
koCa Baseline activation rate constant for the RyR without luminal SR Ca2+ dependence
kleak SR Ca2+ leak rate constant
VmaxSRCaP Vmax of SERCA pump
ec50SR EC50 for luminal Ca2+ dependence of the RyR
Kmf Km for SERCA pump in forward mode