Figure 6. Expression of familial PD genes is altered in degenerating neurons of vSNc.

Double immunofluorescence staining against TH (green) and (A) DJ-1 (red) or (B) Pink1 (red) or (C) Lrrk2 (red) in SNc of control and 1 y-old Rgs6 ^−/− mice that display dysmorphic TH^low mDA neurons. Arrowheads indicate unaffected neurons while arrows point to TH^low cells. Scale bar 20 µm.