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. 2014 Dec 11;10(12):e1004851. doi: 10.1371/journal.pgen.1004851

Figure 4. Cbx8 target genes are PRC1 target genes in self-renewing ES cells.

Figure 4

(A) Cbx8-enriched GO categories are visualized using REVIGO [48] which allows to cluster GO according to their similarity in a semantic space. Only GO categories with an adjusted P-value of 0.001 or less are shown using “medium” for the allowed semantic similarity. (B) ChIP-seq profiles of H3K27me3, Ring1b, Cbx7 and Cbx8 in ES cells in self-renewing conditions and of Cbx8 and IgG in RA-treated ES cells are shown using the UCSC genome browser. (C) Venn diagram showing the overlap of Cbx8 target genes in RA-treated cells with those of Cbx7 in untreated, self-renewing ES cells.