Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Dec 11;10(12):e1004866. doi: 10.1371/journal.pgen.1004866

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2014 Warburton-Pitt et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

(A) klp-11 single mutants are not Dyf. klp-11 is SynDyf with arl-13, which is partially suppressed by deletion of hdac-6. (B) unc-119 single mutants are moderately Dyf. unc-119 is SynDyf with both klp-11 and nphp-2. unc-119; hdac-6; nphp-2 triple mutants exhibit suppression of the unc-119 Dyf phenotype. (C) Diagram of interactions between klp-11, arl-13, nphp-2, unc-119, and hdac-6, and between DR and TZ genes, based on SynDyf phenotypes presented in panels A and B and in Fig. 1 and S5 Figure. The T-bar indicates hdac-6 mediated suppression of SynDyf phenotypes. Data was analyzed with pairwise Mann-Whitney U-test between wild type, double mutants, and their respective single mutants, followed by the Holm-Bonferroni multiple comparison adjustment. *, significant versus single mutants at a total alpha of 0.05. **, significant versus single mutants at a total alpha of 0.01. nphp-2, arl-13, hdac-6, and arl-13; hdac-6 Dyf data is presented in Fig. 1.