Table 3. Details of Bevacizumab Treatment and Response.
Patient No | Site of target lesion(s) | Largest target lesion (cm) | Concurrent chemotherapy regimen | Dosage of bevacizumab | No. cycles of bevacizumab | Response |
---|---|---|---|---|---|---|
1 | Liver | 6.1 | None | 7 mg/kg IV every 2 weeks | 3 | Progression |
2 | Abdomen | 18 | Carboplatin/paclitaxel; liposomal doxorubicin | 5 mg/kg IV every 3 weeks | 10 | Stable |
3 | Liver | 4.2 | Gemcitabine, then leuprolide acetate; docetaxel | 7.5 mg/kg IV every 2 weeks | 12 | PR |
4 | NMD | N/A | Etoposide | 7 mg/kg IV every 2 weeks | 6 | Progression |
5 | Colon | 3.2 | Carboplatin/paclitaxel; paclitaxel | 7 mg/kg IV every 4 weeks | 12 | PR |
6 | Cul-de-sac | 7.4 | None | 10 mg/kg IV every 2 weeks | 6 | CR |
7 | Liver | 5 | Paclitaxel | 5 mg/kg IV every 2 weeks | 2 | Stable |
8 | Liver | 12.5 | None | 15 mg/kg IV every 3 weeks | 3 | Progression |
NMD: no measurable disease; IV: intravenously; PR: partial response; CR: complete response