Table 4. Details of Response and Follow-up for Patients Treated with Bevacizumab.
Patient No. | Response | Characteristics of response | Patient status |
---|---|---|---|
1 | CR | 7.4 cm vaginal apex mass, resolved after RT/bevacizumab | NED at 8.5 months after start of bevacizumab |
2 | PR | Upper abdominal disease and liver mass, stable when bevacizumab was combined with gemcitabine, progression when bevacizumab was combined with leuprolide acetate, and PR when bevacizumab was combined with docetaxel | AWD 25.5 months after start of bevacizumab |
3 | PR | PR of abdominopelvic disease with eventual progression | AWD 13.5 months after start of bevacizumab |
4 | Stable | Stable disease when combined with paclitaxel and carboplatin or combined with liposomal doxorubicin | AWD 21.6 months after start of bevacizumab |
5 | Stable | Mixed response with decrease in liver lesions but increase in peritoneal implant and ascites; did not meet criteria for response or progression | DOD 9.4 months after start of bevacizumab |
6 | Progression | Peritoneal implant, lung metastasis, and diaphragmatic lymph node involvement progressed at 3 months | AWD 25.7 months after start of bevacizumab |
7 | Progression | Progression in liver and lung | AWD 37.3 months after start of bevacizumab |
8 | Progression | Abdominopelvic disease progressed; liver lesion decreased but likely owing to recent liver RT and so considered progression | DOD 28.9 months after start of bevacizumab |
CR: complete response; RT: radiotherapy; PR: partial response; NED: no evidence of disease; AWD: alive with disease; DOD: died of disease