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. 2014 Dec 15;25(25):4195–4204. doi: 10.1091/mbc.E14-08-1285

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© 2014 Plak et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

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FIGURE 2: — Hyperactivation of Rap1 leads to various cytokinetic defects on substrates. Dictyostelium Rap1G12V (+DOX) and control (−DOX) cells. Shown are (A) graph depicting the average cell size of vegetative grown cells and (B–F) images of cells undergoing cytokinesis on substrates; time in seconds is indicated. Arrows in F show the regions where the furrow is being formed. Scale bars: 10 μm. * indicates significantly different from wild type with p < 0.01.