Figure 6. MSL-complex has affinity to repeats.

(A) Percentage of repeat masked sequences (from UCSC), in 20 bins of 1 kb distance from the transcription start site (TSS) of X-chromosome expressed genes, autosomal expressed genes, MSL1-bound/unbound genes in roX mutants, on the X-chromosome and on autosomes. Rectangles represent the mean values of repeats for all expressed genes in each distance bin, and error bars indicate 95% confidence interval. (B) DNA-FISH with a probe against the mini-white gene combined with MSL2 immunostaining, on polytene chromosomes of wild type and roX mutant males. C2 is a cluster of seven tandemly repeated copies of P[lacW] transgene, the 1A-6 cluster consists of two copies. Note that the transgene cluster consisting of seven copies recruits MSL2 in a roX mutant background. The site of the construct insertion is indicated by arrows.