Table 2. Multivariate analysis RP11-570L13.

	Disease free survival					Overall survival
	n	(%)	HR	(95% CI)	P value	n	(%)	HR	(95% CI)	P value
Age
≤62.3	70	(50.4)		reference		77	(49.4)		reference
>62.3	69	(49.6)	1.03	(0.65–1.62)	0.895	79	(50.6)	1.19	(0.74–1.90)		0.482
Gender
female	43	(30.9)		reference		50	(32.1)		reference
male	96	(69.1)	1.03	(0.62–1.71)	0.905	106	(67.9)	1.45	(0.85–2.48)		0.177
Margins
R0	117	(84.2)		reference		134	(85.9)		reference
R1	22	(15.8)	1.39	(0.74–2.62)	0.301	22	(14.1)	1.85	(0.99–3.48)		0.056
Grading
G1/2	77	(55.4)		reference		89	(57.1)		reference
G3/4	62	(44.6)	1.84	(1.20–2.83)	0.005	67	(42.9)	2.21	(1.40–3.47)		0.001
UICC stage
I	65	(46.8)		reference		73	(46.8)		reference
II	29	(20.9)	1.85	(1.04–3.27)	0.035	37	(23.7)	1.76	(0.96–3.21)		0.067
III	32	(23.0)	2.94	(1.59–5.45)	0.001	33	(21.2)	2.63	(1.39–4.96)		0.003
IV	13	(9.4)	3.52	(1.70–7.27)	0.001	13	(8.3)	4.21	(1.95–9.07)		<0.001
Aberration
normal	90	(64.7)		reference		101	(64.7)		reference
loss	42	(30.2)	1.77	(1.10–2.84)	0.019	46	(29.5)	2.20	(1.33–3.64)		0.002
gain	7	(5.0)	1.01	(0.39–2.65)	0.978	9	(5.8)	0.88	(0.33–2.34)		0.801

Cox regression hazard model was used for multivariate analysis to assess the prognostic value of aberrations.

HR, hazard ratio; CI, confidence interval; UICC, Union for International Cancer Control.