. 2014 Dec 11;9(12):e113687. doi: 10.1371/journal.pone.0113687

Table 4. Relative integrals (%)¹ from selected plasma metabolites in piglets of all groups.

Metabolites		Relative integrals (%)¹				SEM	P-value
		NC	DON	GLU	DG
HDL(δ0.83)	CPMG	1.971^b	1.751^c	2.270^a	2.007^ab	0.091	<0.01
	Standard 1D	1.926^a	1.814^b	1.948^a	1.848^b	0.014	<0.01
LDL (δ0.84)	CPMG	1.010^b	1.266^a	0.964^b	1.261^a	0.036	<0.01
	Standard 1D	1.001^b	1.062^a	0.992^b	1.051^a	0.008	<0.01
Alanine (δ1.48)	CPMG	1.033^b	1.237^a	0.980^b	1.016^b	0.026	<0.01
	Standard 1D	1.013^b	1.040^a	1.003^bc	0.993^c	0.005	<0.01
Arginine (δ1.63)	CPMG	0.502^b	0.658^a	0.499^b	0.610^ab	0.022	<0.01
	Standard 1D	1.249^b	1.314^a	1.248^b	1.304^a	0.009	<0.01
Acetate (δ1.92)	CPMG	0.172^b	0.218^a	0.194^b	0.173^b	0.005	<0.01
	Standard 1D	0.310^b	0.318^a	0.320^ab	0.318^ab	0.005	0.168
Proline(δ2.00)	CPMG	1.204^a	0.987^b	1.185^a	1.083^ab	0.024	<0.01
	Standard 1D	1.478^a	1.408^c	1.486^a	1.450^b	0.008	<0.01
Glycoprotein (δ2.05)	CPMG	2.190^b	2.766^a	2.254^b	2.630^a	0.063	<0.01
	Standard 1D	1.461^c	1.593^a	1.460^c	1.513^b	0.014	<0.01
Citrate (δ2.52)	CPMG	0.196^a	0.166^b	0.187^a	0.197^a	0.004	<0.01
	Standard 1D	0.463^a	0.451^b	0.464^a	4.681^a	0.002	<0.01
TMAO (δ3.26)	CPMG	0.575^b	0.811^a	0.549^b	0.613^b	0.029	<0.01
	Standard 1D	0.169^b	0.227^a	0.184^b	0.183^b	0.006	<0.01
Glycine (δ3.56)	CPMG	1.179^b	1.439^a	1.237^b	1.242^b	0.028	<0.01
	Standard 1D	0.343^b	0.380^a	0.347^b	0.337^b	0.005	<0.01
Lactate (δ4.11)	CPMG	2.462^bc	3.817^a	2.316^c	3.154^ab	0.158	<0.01
	Standard 1D	1.289^b	1.549^a	1.234^b	1.260^b	0.034	<0.01
Unsaturated lipids (δ5.31)	CPMG	0.706^a	0.576^b	0.712^a	0.678^ab	0.018	0.014
	Standard 1D	0.757^a	0.640^c	0.781^a	0.679^b	0.014	<0.01
Urea (δ5.78)	CPMG	0.178^b	0.271^a	0.178^b	0.244^a	0.010	<0.01
	Standard 1D	0.165^c	0.212^a	0.179^b	0.204^a	0.005	<0.01
Fumarate (δ6.52)	CPMG	0.0061^a	0.0033^b	0.0061^a	0.0057^a	0.00003	<0.01
	Standard 1D	0.028^a	0.026^b	0.028^a	0.028^a	0.000	0.016
Glutamate/ Creatinine	CPMG	3.300^b	4.152^a	3.352^b	3.435^b	0.086	<0.01
	Standard 1D	3.265	3.253	3.252	3.248	0.023	0.995

Data are presented as means ± SEM, n = 5 for treatments, with a-c used to indicate statistically significant difference (P<0.05, one way ANOVA method). Normalized integral of metabolites in spectrum (normalized to 100, chemical shift region over the ranges of δ 0.5–4.55 and δ 5.13–8.5.

Dietary treatments were NC, an uncontaminated basal diet, DON, the basal contaminated with 4 mg/kg deoxynivalenol, GLU, uncontaminated basal diet with 2% glutamic acid supplementation, and DG, deoxynivalenol-contaminated (4 mg/kg) basal diet with 2% glutamic acid supplementation (n = 5).

Table 4. Relative integrals (%)1 from selected plasma metabolites in piglets of all groups.

Table 4. Relative integrals (%)¹ from selected plasma metabolites in piglets of all groups.