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Impact of mutating protease targets genes on biofilm formation. Biofilm formation was assessed in UAMS-1 (WT) and isogenic derivatives with mutations in sarA, spa, fnbA, or ica. It should be noted that UAMS-1 does not encode fnbB (Cassat et al. 2005). Single asterisk indicates statistical significance by comparison to the parent strain. Double asterisks indicate statistical significance by comparison to the isogenic ica mutant.
