Table 2. Protein regulation in SW480 and HT29 after treatment with 5 µM Ciglitazone as determined by 2D-PAGE autoradiography scans.
SW480 | HT29 | ||||
Protein | Acc.No. | Diff. | p-value | Diff. | p-value |
Heat-shock protein 105 kDa | Q92598 | 6,24 | 0,002 | 1,437 | 0,488 |
FK506-binding protein 4 | Q02790 | 5,547 | 0,040 | 1.673 | 0,416 |
T-complex protein 1, theta subunit | P50990 | 3,806 | 0,004 | 4,142 | 0,017 |
Heat shock 70 kDa protein 1 | P08107 | 3,649 | 0,037 | 3,641 | 0,016 |
Stress-70 protein | P38646 | 3,573 | 0,007 | 4,162 | 0,005 |
Endoplasmin | P14625 | 3,505 | 0,03 | 2,177 | 0,067 |
Protein disulfide-isomerase A3 | P30101 | 3,133 | 0,01 | 2,494 | 0,241 |
Tryptophanyl-tRNA synthetase | P23381 | 3,074 | 0,034 | 4,214 | 0,017 |
Transitional endoplasmic reticulum ATPase | P55072 | 3,046 | 0,023 | 1,964 | 0,056 |
T-complex protein 1, beta subunit | P78371 | 1,644 | 0,048 | 3,104 | 0,019 |
Proteins upregulated more than three-fold with statistical significance (p<0.05) are indicated by bold letters. Proteins involved in chaperoning functions are displayed in italic font.