Figure 9. Contributions of each of the MR protocols (normalized between 0 and 1) in (a) capturing treatment changes post-LITT at 24-hour, 1-month, 3-month, and 6-month time periods for epilepsy, and (b) differentiating successful treatment and tumor recurrence at 24- hour, 2-month, 4-month, 6-month, 9-month, and 11-month post-LITT for GBM studies.

Fig. 9(a) illustrates that T1w MRI and T2-GRE were most discriminative in distinguishing patients with successful treatment and tumor recurrence across all time-points, as compared to T2w MRI, and FLAIR. Similarly, Fig. 9(b) suggest that ADC was identified as being most reflective of early treatment changes (up to 3-months), while T1w was found to be more reflective of early delayed treatment changes (1-month, 3-months) compared to the other protocols under evaluation.