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. 2014 Dec 15;745:176–181. doi: 10.1016/j.ejphar.2014.10.041

Fig. 1.

Fig. 1

Identification of hits and target on HMDM using the xCELLigence (a) initial screen of 61 peptides at 8 μM on HMDM (n=4–6). Asterisk indicates P<0.001. Bars are shaded according to peptide length (see Supplementary Table 2), (b) dose–response curves for peptides on HMDM (n=3–5), (c) dose-dependent antagonism of response using C3a receptor antagonist SB 290157 (SB) when agonized with the EC50 concentrations of hits (n=3–5), and (d) dose-dependent antagonism of response using C5a1 antagonist PMX53 when agonized with the EC50 concentrations of hits (n=3–5).