Table 4. Univariate and multivariate generalized estimating equations model of factors associated with HIV-1 viral loads.
Univariate | Multivariate model I | Multivariate model IIa | |||||
No. | difference | p | difference | p | difference | P | |
Gender | |||||||
Male | 603 | ||||||
Female | 38 | −26767.8 | <0.001 | −20826.2 | 0.013 | −26658.9 | <0.001 |
Age (yrs) | |||||||
<30 | 286 | ||||||
30–50 | 290 | −4936.2 | 0.449 | 1520.8 | 0.823 | −3313.5 | 0.633 |
≥50 | 48 | −4747.7 | 0.627 | 2665.1 | 0.802 | 8246.7 | 0.404 |
Mode of transmission | |||||||
Homosexual contact | 371 | ||||||
Heterosexual contact | 70 | −3605.2 | 0.706 | 10465.9 | 0.387 | - | - |
Injecting drug use | 128 | −22329.5 | <0.001 | −73432.1 | <0.001 | - | - |
Receipt of blood products | 6 | −7205.5 | 0.752 | −35456.4 | 0.227 | - | - |
HIV-1 subtype | |||||||
B | 217 | ||||||
C | 3 | 1607.7 | 0.940 | 23058.5 | 0.269 | 19596.9 | 0.325 |
CRF01_AE | 16 | −10620.5 | 0.291 | −43785.9 | 0.004 | −37612.3 | 0.004 |
CRF07_BC | 30 | −21153.8 | 0.005 | −9074.4 | 0.472 | −58045.6 | <0.001 |
CRF08_BC | 1 | −7883.3 | 0.086 | −113409.7 | <0.001 | −106777.7 | <0.001 |
CD4 cell count (cells/mm3) | |||||||
≤50 | 22 | ||||||
51–250 | 82 | −263241.1 | <0.001 | −240696.2 | <0.001 | −246030.4 | <0.001 |
251–500 | 209 | −313911.1 | <0.001 | −290801.3 | <0.001 | −296881.6 | <0.001 |
>500 | 160 | −334294.9 | <0.001 | −300993.4 | <0.001 | −309618.0 | <0.001 |
Received ART | |||||||
No | 270 | ||||||
Yes | 371 | −97661.2 | <0.001 | −102574.2 | <0.001 | −88088.5 | <0.001 |
The mode of transmission was removed from multivariate model II.