Table 4. The IPA pathways significantly associated with the differentially expressed transcripts in C. perfringens/E. maxima co-infected Ross chickens compared with uninfected controls.
Ingenuity Canonical Pathway | P Value | Ratio* |
Leukocyte Extravasation Signaling | 1.58E-03 | 7.00E-02 |
Relaxin Signaling | 1.82E-03 | 6.96E-02 |
LPS/IL-1 Mediated Inhibition of RXR Function | 2.29E-03 | 5.83E-02 |
Pyruvate Metabolism | 2.82E-03 | 5.19E-02 |
Neuroprotective Role of THOP1 in Alzheimer's Disease | 2.88E-03 | 9.26E-02 |
HIF1α Signaling | 2.95E-03 | 8.33E-02 |
ATM Signaling | 7.08E-03 | 1.11E-01 |
HMGB1 Signaling | 7.41E-03 | 8.00E-02 |
Tight Junction Signaling | 8.32E-03 | 6.10E-02 |
ILK Signaling | 9.33E-03 | 6.22E-02 |
Hepatic Fibrosis/Hepatic Stellate Cell Activation | 9.77E-03 | 6.80E-02 |
*The ratio of the number of genes from the dataset mapped to the indicated pathway divided by the total number of genes within that particular pathway.