Skip to main content
. 2014 Dec 11;9(12):e114960. doi: 10.1371/journal.pone.0114960

Table 4. The IPA pathways significantly associated with the differentially expressed transcripts in C. perfringens/E. maxima co-infected Ross chickens compared with uninfected controls.

Ingenuity Canonical Pathway P Value Ratio*
Leukocyte Extravasation Signaling 1.58E-03 7.00E-02
Relaxin Signaling 1.82E-03 6.96E-02
LPS/IL-1 Mediated Inhibition of RXR Function 2.29E-03 5.83E-02
Pyruvate Metabolism 2.82E-03 5.19E-02
Neuroprotective Role of THOP1 in Alzheimer's Disease 2.88E-03 9.26E-02
HIF1α Signaling 2.95E-03 8.33E-02
ATM Signaling 7.08E-03 1.11E-01
HMGB1 Signaling 7.41E-03 8.00E-02
Tight Junction Signaling 8.32E-03 6.10E-02
ILK Signaling 9.33E-03 6.22E-02
Hepatic Fibrosis/Hepatic Stellate Cell Activation 9.77E-03 6.80E-02

*The ratio of the number of genes from the dataset mapped to the indicated pathway divided by the total number of genes within that particular pathway.