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. 2014 Dec 11;9(12):e114895. doi: 10.1371/journal.pone.0114895

Table 1. Proportion of cytokine producing CD4+, CD8+ and DN T cell subsets in various organs from vehicle- and Ang II-infused mice.

IFN-γ TNF-α IL-4 IL-17
Vehicle Ang II Vehicle Ang II Vehicle Ang II Vehicle Ang II
Blood CD4 2.0±0.3 1.7±0.2 14.6±2.8 16.5±2.7 0.5±0.1 0.4±0.1 0.7±0.2 1.1±0.2
CD8 5.5±1.0 7.0 ±12 9.6±2.5 6.8±1.7 0.4±0.1 0.8±0.2 0.4±0.1 0.5±0.1
DN 7.2 ±1.1 12.3 ±2.5 12.0±3.6 9.5±2.5 2.7±0.8 3.1±0.8 7.3±1.2 9.3±1.1
Spleen CD4 3.2 ±0.6 3.4 ±0.3 20.3±3.7 21.3±3.8 1.6±0.1 0.6±0.2 0.6±0.1 0.7±0.2
CD8 5.6 ±1.4 8.23±1.5 13.3±3.2 9.5±2.7 1.1±0.3 0.9±0.2 0.5±0.2 0.5±0.2
DN 13.4 ±2.8 18.1 ±3.0 7.1±1.3 8.8±1.3 3.1±0.9 2.9±0.6 4.1±0.5 3.2±0.4
Aorta CD4 7.4±1.5 6.1±1.4 8.7±2.3 12.9±2.8 0.7±0.2 1.2±0.4 0.8±0.3 1.1±0.3
CD8 2.8±0.6 5.0±0.7 * 2.9±0.6 5.0±1.1 3.0±0.8 3.8±1.0 1.1±0.4 1.7±0.4
DN 3.4±0.9 4.1±1.0 5.2±1.2 6.1±1.4 2.5±1.0 4.7±1.7 5.9±1.7 4.2±0.7
Kidney CD4 5.7±2.2 9.9±2.6 3.6±0.7 3.7±1.1 2.0±0.5 1.7±0.5 1.7±0.3 1.5±0.4
CD8 2.7±1.0 2.6±0.7 5.6±1.5 4.1±1.0 3.4±0.7 2.8±0.7 0.5±0.2 1.5±0.6
DN 4.5±1.5 8.2±1.8 * 3.2±0.6 6.1±3.5 0.7±0.2 1.7±0.5 4.7±1.2 3.7±0.7
Brain CD4 9.0±2.2 8.9±2.2 21.7±3.3 28.4±4.5 0.9±0.3 0.7±0.3 0.4±0.2 0.7±0.3
CD8 11.7±3.1 11.4±2.3 16.4±3.7 13.7±2.6 1.2±0.4 2.9±0.8 1.9±0.6 2.3±0.7
DN 9.5±2.7 14.4±3.2 12.7±3.8 7.4±2.4 2.7±1.5 5.4±1.9 8.7±3.4 8.1±3.7

*P<0.05 Vs Vehicle, Unpaired t –test, n = 11–19.