Figure 6. Lymphocyte infiltration of lungs following oropharyngeal aspiration of B. pseudomallei.

At 24 hour increments, five mice were randomly selected and bronchoalveolar lavage fluid was collected. The number of lymphocytes/BALF were assessed as a measurement of pulmonary inflammation and are presented as the average of the five counts with the SEM presented on the graph. Controls depict lymphocytes from uninfected naïve mice while sham challenged (PBS) samples were harvested 72 hours following inhalation to reflect the timepoint where signs of inflammation were maximal in our studies.