Figure 4. Percent change in RT relative to baseline.
(A) Change in total peripapillary RT for experimental and fellow control eyes in both age groups. The 2-month group experimental eyes exhibit no change in thickness at 1-week, followed by thinning increasing over 2- to 3-weeks, while the 9-month group experimental eyes exhibit increasing thinning from 1- to 3-weeks, The 2 age groups show a similar rate of thinning once it begins, however the 9-month group has greater total thinning because change begins at an earlier time point. (B) Change in total retinal thickness excluding the RNFL (i.e.RGC to BM/RPE layers). Results over the 3-weeks follow up show thinning in experimental eyes similar to the results for total retinal thickness. Error bars = SEM. * indicates p<0.05 when compared to baseline, § indicates p<0.05 when compared to fellow control eyes, † indicates p<0.05 when comparing 2-month and 9-month experimental eyes (Bonferroni). Abbreviations: EXP = experimental eyes, CTRL = fellow control eyes, BL = baseline.
