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. 2014 Dec 11;9(12):e115053. doi: 10.1371/journal.pone.0115053

Figure 10. Caspase-12 silencing enhanced the inhibitory effect of culture supernatants of CSE-exposed Leuk-1 cells on C. albicans.

Figure 10

Antimicrobial activities of culture supernatants of Caspase-12-silenced cells and control cells following CSE treatment were compared. A After the treatment with culture supernatants, C. albicans colonies were observed and counted at 24 h. B The colonies number of C. albicans clearly increased in NC group following the treatment with the culture supernatant of scrambled siRNA-transfected cells exposed to 2%, 4% and 8% CSE. The colonies number of C. albicans following the treatment with the culture supernatant of Caspase-12-silenced cells exposed to 2%, 4% and 8% CSE was remarkably fewer than that in NC group. The colonies number of C. albicans was expressed as means±SE (n = 3). Statistical significance: *P<0.05 vs. culture supernatants of cells not exposed to CSE; #P<0.05, ##P<0.01 vs. culture supernatants of scrambled siRNA-transfected cells.