Skip to main content
. 2014 Dec 11;9(12):e114543. doi: 10.1371/journal.pone.0114543

Table 4. Significant correlations of diffusivity values with neuropsychological variables in patients with ALS.

NPS Variable ROI Diffusivity value with the highest correlation score1 Other diffusivity values with significant correlations
ß Rsqare rs p pFDR
RWT-A CC-B AD 0.411 0.001 0.02
Stroop-I CC-B AD 0.428 0.183 0.001 0.02
ACR R FA −0.433 0.188 0.001 0.02 MD,RD
L RD 0.382 0.146 0.005 0.02 FA,MD
CL R MD 0.409 0.167 0.002 0.02 RD
L RD 0.416 0.173 0.002 0.02 FA
SFOF R MD 0.353 0.125 0.009 0.03
L RD 0.393 0.155 0.004 0.02 FA, MD
UF R MD 0.493 0.243 0.000 0.01 AD,RD
DSB CC-B AD −0.331 0.110 0.005 0.04
ACR R MD −0.309 0.095 0.009 0.04
L FA 0.358 0.128 0.002 0.03 RD MD
SFOF L AD −0.333 0.111 0.005 0.04 MD
VMDR ACR L FA 0.362 0.132 0.002 0.04
VMR CC-B AD −0.370 0.137 0.002 0.03 MD
ACR R MD −0.323 0.104 0.008 0.04 RD
L MD −0.363 0.132 0.003 0.04 RD
UF R RD −0.315 0.099 0.009 0.04
L RD −0.309 0.095 0.011 0.04
RCFT CC-B MD −0.376 0.134 0.012 0.04
ACR R RD −0.472 0.222 0.001 0.01 FA, MD
L RD −0.528 0.278 0.000 0.01 FA, MD
SFOF L RD −0.370 0.137 0.011 0.03 MD
UF R RD −0.395 0.156 0.007 0.02 MD
FrSBe-F-E SLF L RD 0.382 0.146 0.002 0.03
FrSBe-S-E SLF R FA −0.401 0.161 0.004 0.03
L FA −0.384 0.384 0.004 0.03
SFOF R AD 0.449 0.201 0.001 0.01 MD
1

including results of regression analysis and Spearman-rank-correlation respectively (pFDR<0.05)

ROI  =  Region of interest; Stroop-I  =  Stroop-Inhibition; VMDR  =  Verbal Memory Delayed recall; VMR  =  Verbal Memory Recognition; DSB  =  Digit span backward; RCFT  =  Rey complex figure test; FrSBe  =  Frontal System Behaviour Scale; E  =  Executive Dysfunction; S  =  self rating; F  =  family rating; FA  =  fractional anisotropy; MD  =  mean diffusivity; AD  =  axial diffusivity RD  =  radial diffusivity; L  =  Left; R  =  Right; CC-B  =  Body of corpus callosum; CST  =  corticospinal tract; ACR  =  anterior corona radiate; SS  =  sagittal stratum including both the inferior longitudinal fasciculus (ILF) and inferior fronto-occipital fasciculus(IFOF)); CL  =  cingulum; SLF  =  superior longitudinal fasciculus; SFOF  =  superior fronto-occipital fasciculus; UF  =  uncinate fasciculus.