Table 2. Non-synonymous polymorphisms in Gzm genes linked to GzmB on Chr 14 1.
| Gene | Polymorphism3 |
| GzmC | L7I4 |
| E175K (rs266005675) 2 | |
| GzmF | I4V (rs49622871)2 , 4 |
| GzmN | None |
| GzmG | G51R |
| S144T (rs244881887) 2 | |
| GzmD | I4V4 |
| W247R (rs16803648) 2 | |
| GzmE | None |
1
Genes are listed in their correct order on Chr 14, not alphabetically.
2
Previously recorded in various SNP databases.
3
Most of the predicted amino acid changes are highly conservative; unlike GzmB, none are predicted to affect the substrate cleft.
4
Map to the leader sequence, so do not affect the mature protein; a total of four polymorphisms affecting mature protein are shown in bold.