Table 3.
Metabolic factors and markers of subclinical organ damage
| Variable | Obese group (n = 92) | Control group (n = 49) | P value |
|---|---|---|---|
| CfPWV, m/s | 4.84±0.57 | 5.08±0.63 | 0.03 |
| Fasting glucose, mg/dl | 95.5±10.8 | 100.9±10.8 | 0.03 |
| Insulin, µIU/ml | 15.9 (9.5–26.0) | 10.0 (7.1–14.1) | 0.0001 |
| HOMA index | 3.7 (2.3–6.0) | 2.6 (1.8–3.4) | 0.002 |
| Total cholesterol, mg/dl | 162.2 (142.9–181.5) | 142.9 (139.0–158.3) | 0.005 |
| LDL cholesterol, mg/dl | 92.7±27.0 | 77.2±23.2 | 0.0002 |
| HDL cholesterol, mg/dl | 50.2±11.6 | 57.9±11.6 | <0.0001 |
| Triglycerides, mg/dl | 79.6 (53.1–123.9) | 61.9 (44.2–70.8) | 0.0004 |
| Creatinine, µmol/L | 53.3±9.3 | 61.2±11.4 | <0.0001 |
| eGFR, ml/min/1.73m2 | 128.9±18.7 | 114.8±15.9 | <0.0001 |
| Urine albumin, mg/l | 2.1 (0.1–9.5) | 5.1 (0.1–10.0) | 0.33 |
| UACR, mg/g | 1.6 (0.1–6.1) | 2.8 (0.1–5.6) | 0.68 |
Data are mean + SD or median (interquartile range). Because of either hemolysis of blood samples, no shows, or visit delay exceeding 60 days, the total number of blood samples were 79 (86%) in the obese and 47 (96%) in the control group, and the number of urine samples were 88 (96%) in the obese and 46 (94%) in the control group.
Abbreviations: CfPWV, carotid–femoral pulse wave velocity; eGFR, estimated glomerular filtration rate; HOMA index, homeostatic model assessment index; HDL, high-density lipoprotein; LDL, low-density lipoprotein; UACR, urine-albumin-creatinine ratio.