Table 2.
Changes of parameters of metabolic control during the study (pairwise (intra-individual) comparison at beginning vs. at the end of the study), Control and intervention groups (n = 68 subjects with type-1 diabetes mellitus).
| Control group | Intervention group | |||||||
|---|---|---|---|---|---|---|---|---|
| Parameter | At the beginning of the study Mean ± SD | At the end of the study Mean ± SD | Difference Δ Range Variance |
p-value | At the beginning of the study Mean ± SD |
At the end of the study Mean ± SD |
Difference Δ Range Variance |
p-value |
| Number (n) | 34 | 34 | / | / | 34 | 34 | / | / |
| Body weight (kg) | 53.8 ± 13.9 | 54.7 ± 14.3 | 0.91 ± 2.40 10.6 5.7 |
0.035 | 53.7 ± 15.6 | 53.5 ± 15.5 | −0.19 ± 1.59 7.3 2.5 |
0.501 |
| Body-mass Index (BMI) (kg/m2) | 21.8 ± 5.2 | 22.2 ± 5.7 | 0.40 ± 1.04 4.6 1.1 |
0.033 | 20.2 ± 3.7 | 20.1 ± 3.5 | −0.09 ± 0.58 2.6 0.3 |
0.379 |
| Mean amplitude of blood glucose excursions (mmol/L) | 10.7 ± 3.4 | 9.6 ± 3.5 | −1.12 ± 4.23 18.9 17.9 |
0.132 | 8.3 ± 3.2 | 8.5 ± 2.7 | 0.29 ± 3.03 14.9 9.2 |
0.580 |
| HbA1c (%) | 8.96 ± 2.23 | 7.99 ± 1.26 | −0.98 ± 1.45 7.7 2.2 |
0.001 | 8.84±1.71 | 8.12±1.10 | −0.72±1.48 6.0 1.2 |
<0.001 |
| Insulin dose (I.U.) | 47.3±18.3 | 46.3±17.8 | −0.99±10.37 41.5 107.5 |
0.581 | 45.5±24.2 | 47.0 ± 24.4 | 1.57 ± 15.84 88.5 251.1 |
0.646 |
| Insulin dose per kg body weight (I.U./kg body weight) | 0.89 ± 0.33 | 0.88 ± 0.32 | −0.02 ± 0.04 0.16 0.001 |
0.008 | 0.86 ± 0.44 | 0.87 ± 0.44 | 0.002 ± 0.03 0.18 0.001 |
0.566 |