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. 2014 Oct 7;124(25):3799–3807. doi: 10.1182/blood-2014-04-569392

Table 1.

Intrinsic dissociation rate constants (k0off) and reactive compliance (σ) values for WT and mutant murine GPIbα–VWF-A1 tether bonds

Mouse rVWF–A1 k0off (s−1) σ (nm) R2
WT 3.05 ± 0.55 0.028 ± 0.001 0.97
R1326H 7.80 ± 1.15 0.039 ± 0.002 0.93
I1309V 0.49 ± 0.04 0.020 ± 0.003 0.95
I1309V, R1326H 4.15 ± 0.67 0.028 ± 0.001 0.94

Values were determined by using statistical MLE of Bell parameters.