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. 2014 Nov 19;145(1):87–95. doi: 10.3945/jn.114.201095

FIGURE 2.

FIGURE 2

Associations (95%) of plasma PLP with one-carbon, tryptophan metabolites and ratios. Associations were modeled by GAMs with use of data from 157 oral contraceptive users. Shaded areas indicate 95% CIs. The significant metabolites, by χ-square test based on GAM, were (A) Hcy, (B) GSH, and the ratios (C) ADMA to Arg, (D) HK to KA, and (E) HK to HAA. ADMA:arg, asymmetric dimethylarginine-to-arginine ratio; GAM, generalized additive model; GSH, glutathione; Hcy, homocysteine; HK:HAA, 3-hydroxykynurenine–to–3-hydroxyanthranilic acid ratio; HK:KA, 3-hydroxykynurenine-to-kynurenic acid ratio; PLP, pyridoxal 5′-phosphate.