Figure S5.

Liraglutide reduces VLDL-cholesterol without changes in weight. (A) C57BL/6J mice on a chow diet + 4% fructose water for 16 weeks were given a once daily intraperitoneal (ip) injection of vehicle or liraglutide (20 μg/kg) during the final 4 weeks. On the final day, an ip injection of poloxamer (0.5 g/kg) was administered following a 5 h fast. (B) Body weight was measured for the duration of the study (16 weeks). (C) VLDL-cholesterol levels 6 h after poloxamer. n = 3. Analyzed by two-way ANOVA with Bonferroni post hoc test (B) or by Student's unpaired t-test (C).