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. 2014 Oct 24;15(11):19394–19405. doi: 10.3390/ijms151119394

Figure 7.

Figure 7

Anti-miR-200 can reverse the effect of catalpol. Anti-miR-200 could evidently decrease the expression of miR-200 in OVCAR-3 cells (A); After treatment with catalpol (50 μg/mL) for 48 h, anti-miR-200 significantly promoted the cell proliferation of OVCAR-3 cells (B); After treatment with catalpol (50 μg/mL) for 48 h, anti-miR-200 evidently inhibited cell apoptosis of OVCAR-3 cells (C) and the anti-miR-200 significantly increased MMP-2 activity in OVCAR-3 cells after catalpol (50 μg/mL) treatment at 48 h (D). * p < 0.01 compared with 0 mg/mL catalpol treatment group, and # p < 0.01 compared with catalpol-treated group transfected with negative control.