Table 1.
Makers | Allele Frequency (%) | p-Value a | OR b (95% CI) | Genotype Frequency (%) | p-Value a | HWE p-Value | Models | OR b (95% CI) | p-Value a | ||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SNPs | ID | ||||||||||||
SNP1 | rs6943555 | A | T | 0.097 | AA | AT | TT | 0.001 | 0.496 | ||||
SCZ | 33.0 | 77.0 | 1.191 | 7.8 | 50.5 | 41.7 | Dominant | 1.363 (0.848–2.191) | 0.001 | ||||
CTR | 29.3 | 70.7 | (0.969–1.463) | 10.4 | 37.9 | 51.7 | Recessive | 0.734 (0.456–1.180) | 0.201 | ||||
Addictive | 1.197 (0.971–1.475) | 0.093 | |||||||||||
SNP2 | rs7459368 | G | A | 0.720 | GG | AG | AA | 0.809 | 0.954 | ||||
SCZ | 17.4 | 82.6 | 1.047 | 2.7 | 29.5 | 67.8 | Dominant | 1.117 (0.495–2.523) | 0.809 | ||||
CTR | 16.8 | 83.2 | (0.813–1.349) | 3.0 | 27.6 | 69.4 | Recessive | 0.895 (0.396–2.021) | 0.789 | ||||
Addictive | 1.048 (0.813–1.351) | 0.719 | |||||||||||
SNP3 | rs9886351 | G | A | 0.681 | GG | AG | AA | 0.803 | 0.114 | ||||
SCZ | 27.4 | 72.6 | 0.956 | 8.3 | 38.3 | 53.4 | Dominant | 1.028 (0.632–1.672) | 0.803 | ||||
CTR | 26.6 | 73.4 | (0.771–1.185) | 8.5 | 36.1 | 55.4 | Recessive | 1.067 (0.662–1.719) | 0.789 | ||||
Addictive | 1.030 (0.825–1.286) | 0.794 |
SCZ: schizophrenia; CTR: control; OR: odds ratio; CI: confidence interval; SNP1: rs6943555; SNP2: rS7459368; SNP3: rS9886351; HWE: Hardy–Weinberg equilibrium. Significant p-values and HWE p-values were shown in bold font. a: p-values were based on normal chi-square statistics; b: OR refers to the risk allele odds ratio for both the cases and controls.