Figure 1.

Effect of Dexamethasone on DNA synthesis and cell growth. (a) Incorporation of ³H-thymidine in non-Hodgkin’s T cell human lymphoblastic lymphoma cell line (SUP-T1) cells. Cells were cultured for 48 h without (C = control sample) or with 100 Dex. 1 µCi ³H-tymidine was added to the medium 2 h before the analysis. The radioactivity was evaluated on extracted nucleic acid in each preparation. The data are expressed as cpm/mg DNA and represent the mean ± S.D. of 3 independent experiments performed in duplicate. (Significance, * p < 0.001 versus 0 h); (b) Count of cell number. The data are expressed as cell number/mL and represent the mean ± S.D. of 3 independent experiments performed in duplicate. (Significance, * p < 0.001 versus control sample).