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Cytotoxicity of Ch2-PEGn and Ch2-PEGn-CLs on SKOV-3 cells by the MTT assay (Mean ± SD, n = 4–6). (A) IC50 values for Ch2-PEG600, Ch2-PEG1000 and Ch2-PEG2000 were about 78, 145 and 127 μM, respectively; (B) IC50 values for CLs, Ch2-PEG600-CLs, Ch2-PEG1000-CLs and Ch2-PEG2000-CLs were about 38, 100, 143 and 302 μM, respectively. The cytotoxicity of CLs was reduced by introducing Ch2-PEGn into Ch2-PEGn-CLs.
